Advances in Diabetes: Novel insights

DETAILS : 

• Author : GR Sridhar 
  
• Publisher ‏ : ‎ Jaypee Brothers Medical Publishers
  
• Publication date ‏ : ‎ 1 January 2016
  
• Edition ‏ : ‎ First Edition
  
• Language ‏ : ‎ English
  
• Paperback ‏ : ‎ 225 pages
  
• ISBN-10 ‏ : ‎ 9351526453
  
• ISBN-13 ‏ : ‎ 978-9351526452
  
• Item Weight ‏ : ‎ 350  g

ABOUT THE BOOK

Advances in Diabetes: Novel Insights, authored by the highly distinguished endocrinologist and researcher Prof. Dr. G.R. Sridhar and published by Jaypee Brothers Medical Publishers, is a cutting-edge, state-of-the-art clinical compendium. The book serves as a vital bridge between rapid molecular laboratory discoveries, bioinformatics, and the real-world clinical management of metabolic disorders.

The primary objective of the volume is to unpack the massive paradigm shifts currently reshaping our understanding of Diabetes Mellitus. Rather than restating basic clinical guidelines, Dr. Sridhar aggregates high-level research data to explore the complex, multi-systemic nature of the disease. The book is structured around several evolutionary frontiers in diabetology:

• Bioinformatics and Systems Biology: Explores how computational biology, machine learning models, and big data are being utilized to map the intricate cellular networks, genetic predispositions, and signaling pathways underlying insulin resistance.
• The Omics Revolution: Investigates the roles of genomics, transcriptomics, metabolomics, and proteomics in predicting diabetic complications before they physically manifest, paving the way for hyper-personalized medicine.
• The Gut-Brain-Metabolism Axis: Details novel insights into how the gut microbiota, incretin hormones (like GLP-1 and GIP), and central nervous system signaling interact to regulate glucose homeostasis and energy balance.
• Cardio-Renal-Metabolic Integration: Analyzes the shared pathophysiological pathways linking Type 2 Diabetes with heart failure and chronic kidney disease, highlighting the protective molecular mechanisms of newer drug classes like SGLT2 inhibitors and GLP-1 receptor agonists.
• Cognitive Dysfunction and Diabetes: Delves into the emerging, critical research field linking chronic hyperglycemia and insulin resistance to neurodegenerative conditions, often referred to in modern research as "Type 3 Diabetes."

The text is heavily enhanced with highly detailed biochemical flowcharts, multi-omic mapping diagrams, and comparative therapeutic matrices. This transforms the work into an essential, advanced masterclass for endocrinologists, diabetologists, post-graduate medical students, and translational researchers seeking to stay at the absolute forefront of metabolic medicine.

ABOUT THE AUTHOR

Prof. Dr. G.R. Sridhar is a pioneering Indian endocrinologist, researcher, and the founder-director of the Endocrine and Diabetes Centre in Visakhapatnam, Andhra Pradesh. He is widely recognized for his groundbreaking work in applying bioinformatics to endocrinology and has served in top-tier leadership positions, including past President of the Endocrine Society of India (ESI) and the Research Society for the Study of Diabetes in India (RSSDI).

Dr. Sridhar’s authorial style is characterized by deep intellectual curiosity, scientific rigor, and an exceptional ability to make complex molecular biology completely accessible to practicing clinicians. He is a prolific writer with hundreds of peer-reviewed research publications in international journals and serves on the editorial boards of numerous prestigious medical publications. Through his continuous literary and clinical contributions, he remains a key driving force behind modernizing diabetes research in South Asia.